This item contains a signature of Ernst Adolf Coccius (b.1825, d.1890), a German ophthalmologist who was a native of Knauthain (Leipzig) and served as Director of the Leipzig Eye Clinic from 1867 to 1890. In 1853, Coccius provided the first description of retinal breaks of the eye, making the association to retinal detachment and he devised an ophthalmoscope that was a modification of the device invented by Hermann von Helmholtz. Autograph collected by by David S. Light, M.D. as part of the Light collection of scientific letters. The collection was donated to the Rudolph Matas Library of the Health Sciences between 1993 and 2003. David S. Light, M.D. (alumnus, Tulane University School of Medicine, 1944).