This item contains a signature of Claude Bernard (b.1813-d.1878), a French physiologist. The intimate connection between the brain and the heart was enunciated by Claude Bernard. He studied the chemical and physiological study of digestion and liver function, along with experimental section of nerves and studies on sympathetic nerves. For more information search PubMed: http://www.ncbi.nlm.nih.gov/pubmed?term=Bernard+C[PS] . Autograph collected by by David S. Light, M.D. as part of the Light collection of scientific letters. The collection was donated to the Rudolph Matas Library of the Health Sciences between 1993 and 2003. David S. Light, M.D. (alumnus, Tulane University School of Medicine, 1944).