Understanding the mechanisms that promote rapid phenotypic divergence in adaptive color-patterns affords valuable insights into understanding patterns of biodiversity. My research has emphasized divergence in coloration and patterning by focusing primarily on aposematic species where color-pattern is not only used as an anti-predatory signal, but has also been coopted to influence female mate choice and male/male conflict. My dissertation research was grounded firmly in behavioral ecology, studying the evolutionary ecology of adaptation. I focused on two main scales of interactions between poison frogs and their local habitats. The first looked at the fine-scale influence of the frog’s microhabitat in shaping aposematic signaling using a multi-trophic level approach. The second scale broadly sought to identify isolating barriers between phenotypically distinct populations.